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Histone Modifications: Epigenetic Mediators of Environmental Exposure Memory

Jan 7, 2019
1 min read

How organisms retain a memory of ancestral environmental exposure is a phenomenon that is still poorly understood. Recently published work by our group and others, regarding environmentally induced transgenerational effects, have identified an array of mechanisms, with a particular focus on histone modifications, that shed some light on the underlying epigenetic processes driving long-term generational effects.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6233965/

218 Comments


goudan fu
goudan fu
5 days ago

I rewrote my lab notebook template to separate histone-mark persistence from DNA methylation, after the IGF2 example made the two tracks impossible to lump together. In the new template, each exposure gets a column for generation of fade and one for confounders. I plugged the Jan 7, 2019 dates into a small garden-calculator-style tracker to map which marks survived to F2 before drafting follow-up questions.

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Lonely Monda
Lonely Monda
Oct 29

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ali88 kiki88
ali88 kiki88
Oct 22

Mình có lần lướt đọc mấy trao đổi trên mạng شيخ روحاني thì thấy nhắc nên cũng tò mò mở ra xem thử cho biết. Mình không tìm hiểu sâu جلب الحبيب chỉ xem qua trong thời gian ngắn để quan sát bố cục جلب الحبيب cách sắp xếp شيخ روحاني các mục và trình bày nội شيخ روحاني dung tổng thể. Cảm giác là các phần được trình bày khá gọn, các Huren Berlin mục rõ ràng nên đọc lướt cũng không bị rối với mình như Hurentest Berlin vậy là đủ để nắm tin cơ bản rồi. جلب الحبيب

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Oct 15

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